Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427682 | 1.00 | ACHE (0.43) | ACHENOD2NOD1CRHBPCRHR2 | |
| SCHEMBL9427779 | 0.91 | ACHE (0.44) | ACHENOD2NOD1CRHBPCRHR2 | |
| SCHEMBL9427847 | 0.83 | ACHE (0.48) | ACHECRHBPCRHR2PPARG | |
| SCHEMBL9427575 | 0.82 | ACHE (0.46) | ACHECRHBPCRHR2 | |
| SCHEMBL9427707 | 0.77 | AGTR1 (0.49) | NOD2NOD1SMN1; SMN2TDP1 | |
| SCHEMBL9427712 | 0.77 | AGTR1 (0.49) | NOD2NOD1SMN1; SMN2TDP1 | |
| SCHEMBL9427691 | 0.74 | ACHE (0.49) | ACHEPPARG | |
| SCHEMBL7299126 | 0.73 | AGTR1 (0.59) | PPARG | |
| SCHEMBL7302764 | 0.73 | AGTR1 (0.51) | PPARG | |
| SCHEMBL7301911 | 0.73 | AGTR1 (0.48) | ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315013-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| US-5189048-A | Hypotensive agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-5093346-A | Hypotensive agents, congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5081127-A | Hypotensive agents and treatment of congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-5043349-A | Hypotensive agents, treatment of congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
| US-5015651-A | Triazole derivatives for treatment of congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-14 | — | — | US | disclosed |