Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636998 | 0.83 | SNCA (0.49) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL9428199 | 0.80 | NOX1 (0.46) | MAPTMEN1KMT2AALDH1A1NOX1 | |
| SCHEMBL5020109 | 0.77 | MEN1 (0.49) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL10501378 | 0.68 | MAPT (0.47) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL225916 | 0.65 | MAPT (0.59) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL29640485 | 0.65 | MAPT (0.59) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL9813295 | 0.63 | MAPT (0.44) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL2609258 | 0.62 | NOX1 (0.66) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL239549 | 0.61 | NOX1 (0.65) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL7667435 | 0.60 | MAPT (0.47) | MAPTMEN1KMT2AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310904-A | Intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0551076-A1 | Process for preparing optically active benzothiazepine compounds by asymmetric reduction | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-14 | — | — | EP | disclosed |