SCHEMBL239549

SCHEMBL239549

Cc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.65
MAPT P10636 7/20 0.65
GAA P10253 6/20 0.65
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
SNCA P37840 4/20 0.65
TDP1 Q9NUW8 3/20 0.65
ALOX15 P16050 3/20 0.65
BCHE P06276 2/20 0.65
ACHE P22303 2/20 0.65
CYP1A2 P05177 1/20 0.65
POLB P06746 1/20 0.65
CYP3A4 P08684 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
ALOX12 P18054 1/20 0.65
MAOA P21397 1/20 0.65
CNR1 P21554 1/20 0.65
PTGS1 P23219 1/20 0.65
SLC6A2 P23975 1/20 0.65
HTR2C P28335 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225916 0.90 MAPT (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29640485 0.90 MAPT (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29321272 0.89 NOX1 (0.52) NOX1MAPTGAAMEN1KMT2A
SCHEMBL225829 0.89 NOX1 (0.65) NOX1MAPTGAAMEN1KMT2A
SCHEMBL2756476 0.86 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL11381973 0.83 MAOA (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL14140472 0.82 NOX1 (0.55) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL9114 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255879-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-14 US claimed
US-20230330095-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-10-19 US claimed
EP-4260861-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR Seoul National University R & DB Foundation (KR) 2023-10-18 EP claimed
EP-0122989-B1 STABILIZED POLYOXYALKYLENE POLYETHER POLYOLS AND POLYURETHANE FOAMS PREPARED THEREFROM ATLANTIC RICHFIELD COMPANY (US) 1987-05-13 EP claimed
EP-0122989-A1 Stabilized polyoxyalkylene polyether polyols and polyurethane foams prepared therefrom ATLANTIC RICHFIELD COMPANY (US) 1984-10-31 EP claimed
US-4444676-A Stabilized polyoxyalkylene polyether polyols and polyurethane foams prepared therefrom ATLANTIC RICHFIELD COMPANY (US) 1984-04-24 US claimed
JP-7138243-A None JP disclosed
US-20250376556-A1 Curable Epoxy Resin Compositions with High Glass Transition Tempature HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2025-12-11 US disclosed
US-20250255879-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-14 US disclosed
EP-4547728-A2 CURABLE EPOXY RESIN COMPOSITIONS WITH HIGH GLASS TRANSITION TEMPERATURE Huntsman Advanced Materials Americas LLC (US) 2025-05-07 EP disclosed
CN-119487097-A Curable epoxy resin composition with high glass transition temperature 亨斯迈先进材料美国有限责任公司 2025-02-18 CN disclosed
WO-2024006101-A2 CURABLE EPOXY RESIN COMPOSITIONS WITH HIGH GLASS TRANSITION TEMPERATURE HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2024-01-04 WO disclosed
US-20230330095-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-10-19 US disclosed
EP-0517656-B1 Fire-protected polyimide composition CIBA GEIGY AG (CH) 1997-08-20 EP disclosed
US-5637387-A PREPOLYMER OF BISMALEIMIDE AND ALKENYLPHENOL STABILIZED WITH PHENOTHIAZINE OR DERIVATIVE THEREOF OR HYDROQUINONE CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
JP-H07138243-A PRODUCTION OF PHENOTHIAZINES KAWAGUCHI KAGAKU KOGYO KK 1995-05-30 JP disclosed
US-5240981-A Blend with alkenylphenol, tribromophenylmaleimide, free radical catalyst, and phenothiazine derivative CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5221764-A During elevated temperature shipping or during storage; adding a cerium compound and a phenylenediamine compound BETZ LABORATORIES, INC. (US) 1993-06-22 US disclosed
EP-0517656-A2 Fire-protected polyimide composition CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
EP-0122989-B1 STABILIZED POLYOXYALKYLENE POLYETHER POLYOLS AND POLYURETHANE FOAMS PREPARED THEREFROM ATLANTIC RICHFIELD COMPANY (US) 1987-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330095-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR NUP205, NUP50, NUP188 NOX1 3666/4885MAPT 2789/4885GAA 2995/4885
US-20250255879-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR NUP205, NUP188, NUP50 NOX1 3568/4885MAPT 2909/4885GAA 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.