Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636998 | 0.91 | SNCA (0.49) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5020109 | 0.85 | MEN1 (0.49) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9427946 | 0.80 | MAPT (0.44) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9171801 | 0.72 | MAPT (0.54) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9427932 | 0.66 | NOX1 (0.45) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10830473 | 0.66 | CACNA1S (0.47) | NOX1MEN1ALDH1A1KMT2ACDYL2 | |
| SCHEMBL10830475 | 0.66 | CACNA1S (0.47) | NOX1MEN1ALDH1A1KMT2ACDYL2 | |
| SCHEMBL10830479 | 0.66 | CACNA1S (0.47) | NOX1MEN1ALDH1A1KMT2ACDYL2 | |
| SCHEMBL12311067 | 0.64 | NOX1 (1.00) | NOX1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9813149 | 0.63 | SNCA (0.61) | NOX1MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310904-A | Intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0551076-A1 | Process for preparing optically active benzothiazepine compounds by asymmetric reduction | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-14 | — | — | EP | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |