Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9429177 | 0.99 | HRH1 (0.45) | HRH1HRH3KDM4EALDH1A1ADRA1A | |
| SCHEMBL9428145 | 0.86 | HRH1 (0.45) | HRH1HRH3ADRA1AADRA1DADRA1B | |
| SCHEMBL9428617 | 0.86 | HRH1 (0.48) | HRH1ALDH1A1ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9428851 | 0.85 | MAPT (0.49) | HRH1ALDH1A1ADRA1AADRA1DADRA1B | |
| Oxalic Acid SCHEMBL9428453 | 0.85 | HRH1 (0.44) | HRH1KDM4EALDH1A1ADRA1AADRA1D | |
| SCHEMBL9428524 | 0.84 | HRH1 (0.49) | HRH1HRH3KDM4EALDH1A1ADRA1A | |
| SCHEMBL9428782 | 0.84 | HRH1 (0.49) | HRH1HRH3KDM4EALDH1A1ADRA1A | |
| Hydrochloric Acid SCHEMBL9428272 | 0.83 | MAPT (0.41) | HRH1HRH3KDM4EALDH1A1ADRA1A | |
| SCHEMBL9428899 | 0.82 | ADRA1B (0.40) | HRH1ALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL9384791 | 0.81 | KDM4E (0.48) | HRH1HRH3KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |