Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 15/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9428453 | 0.98 | HRH1 (0.44) | HRH1METADRA1DADRA1AADRA1B | |
| SCHEMBL9428013 | 0.86 | HRH1 (0.46) | HRH1ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL9429177 | 0.85 | HRH1 (0.45) | HRH1ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL9427995 | 0.83 | MAPT (0.41) | HRH1ADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9428793 | 0.83 | HRH1 (0.40) | HRH1METADRA1DADRA1AADRA1B | |
| SCHEMBL9428295 | 0.83 | KIT (0.46) | HRH1METADRA1AADRA1BABCB1 | |
| SCHEMBL9428874 | 0.82 | HRH1 (0.45) | HRH1ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL9428988 | 0.82 | MAPT (0.45) | HRH1METADRA1AADRA1BABCB1 | |
| Hydrochloric Acid SCHEMBL9429048 | 0.82 | HRH1 (0.40) | HRH1METADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9429503 | 0.82 | MAPT (0.41) | HRH1METADRA1AADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |