Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856022 | 1.00 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9428987 | 0.97 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9428367 | 0.90 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9429047 | 0.88 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9428519 | 0.87 | POLB (0.49) | CYSLTR2CYSLTR1POLB | |
| SCHEMBL9428890 | 0.85 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9855869 | 0.84 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9855870 | 0.84 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9503373 | 0.84 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1POLBBIDBCL2L1 | |
| SCHEMBL9364884 | 0.82 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| JP-1034955-A | — | — | None | — | — | JP | disclosed |
| JP-3024050-A | — | — | None | — | — | JP | disclosed |
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| JP-H0324050-A | LEUKOTRIENE ANTAGONIST | SMITHKLINE BEECHAM CORP | 1991-02-01 | — | — | JP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |