Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9428134 | 0.87 | SMN1; SMN2 (0.70) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL9428166 | 0.82 | CYSLTR1 (0.66) | — | |
| SCHEMBL9186121 | 0.81 | MAOB (0.74) | MRGPRX4MAOBF2 | |
| SCHEMBL6963814 | 0.81 | MAOB (0.69) | ALDH1A1HTTSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL189963 | 0.79 | ELANE (0.73) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL5314324 | 0.77 | ELANE (0.70) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL6520384 | 0.76 | NR4A2 (0.71) | SMN1; SMN2SRD5A2RAB9AMAPTMRGPRX4 | |
| SCHEMBL21508396 | 0.76 | SMN1; SMN2 (0.75) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL9185100 | 0.76 | MRGPRX4 (0.58) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL10352938 | 0.76 | ELANE (0.64) | ALDH1A1HTTSMN1; SMN2SRD5A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497888-A1 | SUBSTITUTED BENZOYLBENZENE-, BIPHENYL- AND 2-OXAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-08-12 | — | — | EP | claimed |
| WO-1991006538-A1 | SUBSTITUTED BENZOYLBENZENE-, BIPHENYL- AND 2-OXAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | claimed |
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5071988-A | Antiu lcer agents, antiallergens cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |