Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.71 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.71 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.71 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.65 |
| ▸ | RXRB | P28702 | 6/20 | 0.62 |
| ▸ | RXRA | P19793 | 5/20 | 0.62 |
| ▸ | RXRG | P48443 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040525 | 0.88 | PTPN1 (0.73) | NR4A2NR4A1NR4A3MRGPRX4SRD5A2 | |
| SCHEMBL26358151 | 0.88 | MEN1 (0.73) | NR4A2NR4A1NR4A3MRGPRX4RAB9A | |
| SCHEMBL6963814 | 0.86 | MAOB (0.69) | MRGPRX4RAB9ANPC1SMN1; SMN2MAPT | |
| Acetic Acid SCHEMBL9428134 | 0.85 | SMN1; SMN2 (0.70) | NR4A2NR4A1NR4A3MRGPRX4SRD5A2 | |
| SCHEMBL1123048 | 0.85 | PKM (0.61) | NR4A2NR4A1NR4A3MRGPRX4SRD5A2 | |
| SCHEMBL10400372 | 0.85 | RAB9A (0.74) | MRGPRX4RAB9APLA2G4BNPC1MAPT | |
| SCHEMBL18546031 | 0.84 | MRGPRX4 (0.69) | NR4A2NR4A1NR4A3MRGPRX4RAB9A | |
| SCHEMBL7791330 | 0.84 | RAB9A (0.62) | MRGPRX4RAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL228477 | 0.83 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2RXRB | |
| SCHEMBL6830467 | 0.83 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| EP-0944584-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023581-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | MPL, CSF3R, CSF1R | NR4A2 632/4885NR4A1 1116/4885NR4A3 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.