Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9428160 | 0.87 | GPBAR1 (0.76) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL9129064 | 0.86 | GPBAR1 (0.82) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL9026288 | 0.86 | GPBAR1 (0.69) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL7599570 | 0.86 | GPBAR1 (0.82) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL10484526 | 0.83 | CYSLTR1 (0.81) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9428141 | 0.82 | ALDH1A1 (0.57) | — | |
| SCHEMBL3271764 | 0.81 | GPBAR1 (0.78) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL8644286 | 0.81 | CYSLTR1 (0.69) | CYSLTR1GPBAR1PDE10ACYSLTR2ALOX5 | |
| SCHEMBL6089995 | 0.80 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL422355 | 0.80 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497888-A1 | SUBSTITUTED BENZOYLBENZENE-, BIPHENYL- AND 2-OXAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-08-12 | — | — | EP | claimed |
| US-5071988-A | Antiu lcer agents, antiallergens cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-10 | — | — | US | claimed |
| WO-1991006538-A1 | SUBSTITUTED BENZOYLBENZENE-, BIPHENYL- AND 2-OXAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | claimed |
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5071988-A | Antiu lcer agents, antiallergens cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |