Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305779 | 0.97 | TOP2A (0.42) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL3808229 | 0.83 | TOP2A (0.32) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL3129267 | 0.83 | TOP2A (0.39) | TOP2ATOP2B | |
| SCHEMBL4300362 | 0.83 | TOP2A (0.39) | TOP2ATOP2BKCNH2 | |
| SCHEMBL8096676 | 0.82 | TOP2A (0.47) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL3136241 | 0.81 | TOP2A (0.47) | TOP2ATOP2BKCNH2 | |
| SCHEMBL10817331 | 0.79 | TOP2A (0.47) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL29219620 | 0.78 | KCNH2 (0.38) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL3138685 | 0.77 | TOP2A (0.35) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL8540093 | 0.77 | KCNH2 (0.41) | TOP2ATOP2BKCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344940-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1994-09-06 | — | — | US | disclosed |