Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | TPMT | P51580 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859656 | 0.86 | CA12 (0.67) | CA12CA1CA2CA4CA6 | |
| SCHEMBL2592749 | 0.86 | CA12 (0.67) | CA12CA1CA2CA4CA6 | |
| SCHEMBL9364255 | 0.85 | MAPT (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2424457 | 0.84 | CA12 (0.65) | CA12CA1CA2CA4CA6 | |
| SCHEMBL9516446 | 0.83 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL30143532 | 0.83 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1251597 | 0.83 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL2784039 | 0.83 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL18280405 | 0.83 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL16664960 | 0.82 | PLK1 (0.49) | HTTTSHRLMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |