Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427574 | 0.73 | TRPV1 (0.60) | EPHX2NR1H4 | |
| SCHEMBL4881597 | 0.71 | EPHX2 (0.60) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL5452234 | 0.71 | SLC22A2 (0.52) | EPHX2NR1H4CYP1A2CYP2C19RAB9A | |
| SCHEMBL3420620 | 0.71 | EPHX2 (0.65) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL178541 | 0.69 | EPHX2 (0.53) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL4403136 | 0.69 | EPHX2 (0.68) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL4618832 | 0.69 | EPHX2 (0.68) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL28822073 | 0.69 | EPHX2 (0.58) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL16443508 | 0.69 | GRIN2B (0.67) | MEN1KMT2ALMNA | |
| SCHEMBL11954 | 0.68 | EPHX2 (0.59) | EPHX2NR1H4HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281625-A | Benzyl substituted guanidine derivatives, salts, and metal complexes | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |
| US-5126374-A | For plants, seeds, soils, effective at low concentrations | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |