Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891340 | 0.86 | EPHX2 (0.68) | TRPV1EPHX2 | |
| SCHEMBL20496896 | 0.84 | MEN1 (0.59) | — | |
| SCHEMBL12049334 | 0.84 | ALOX12 (0.72) | TRPV1 | |
| SCHEMBL12049322 | 0.84 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL12060793 | 0.84 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL4881597 | 0.83 | EPHX2 (0.60) | TRPV1EPHX2NR1H4 | |
| SCHEMBL12049602 | 0.83 | PLA2G1B (0.73) | TRPV1 | |
| SCHEMBL12060869 | 0.83 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL12049595 | 0.81 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL9715376 | 0.80 | TRPV1 (0.58) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407388-B2 | Thiourea derivatives as activators of RORα and pharmaceutical composition containing same | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2019-09-10 | — | — | US | claimed |
| US-10407388-B2 | Thiourea derivatives as activators of RORα and pharmaceutical composition containing same | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2019-09-10 | — | — | US | disclosed |
| US-20180265462-A1 | NOVEL THIOUREA DERIVATIVES AS ACTIVATORS OF RORalpha AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2018-09-20 | — | — | US | disclosed |
| US-5281625-A | Benzyl substituted guanidine derivatives, salts, and metal complexes | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |
| US-5126374-A | For plants, seeds, soils, effective at low concentrations | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265462-A1 | NOVEL THIOUREA DERIVATIVES AS ACTIVATORS OF RORalpha AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | RORA, ROR1, RORB | TRPV1 1486/4885EPHX2 3306/4885NR1H4 15/4885 |
| US-10407388-B2 | Thiourea derivatives as activators of RORα and pharmaceutical composition containing same | RORA, RORB, ROR1 | TRPV1 1308/4885EPHX2 3706/4885NR1H4 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.