SCHEMBL9428689

SCHEMBL9428689

CCCCCCCCON1C(C)(C)CC(C(CCC)Nc2nc(NC(=O)CCC(=O)O)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
ADORA1 P30542 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 2/20 0.30
GLA P06280 1/20 0.30
P2RY12 Q9H244 3/20 0.30
PPARA Q07869 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9429175 0.89 KDM4E (0.35) S1PR1S1PR3NPSR1KDM4EP2RY12
SCHEMBL9428950 0.88 PPARA (0.34) PPARAALDH1A1
SCHEMBL9427923 0.87 KDM4E (0.33) ADORA1KDM4EGLAALDH1A1
SCHEMBL7475738 0.87
SCHEMBL9428301 0.86
SCHEMBL9428916 0.82 SMN1; SMN2 (0.36) NPSR1KDM4EGLAALDH1A1
SCHEMBL7456205 0.82 KMT2A (0.35) ALDH1A1
SCHEMBL9428639 0.82 KMT2A (0.35) ALDH1A1
SCHEMBL9428528 0.82 CDK1 (0.30)
SCHEMBL9428791 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed