SCHEMBL9429175

SCHEMBL9429175

CCCCCCCCON1C(C)(C)CC(C(CCC)Nc2nc(NCCC(=O)O)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
P2RY12 Q9H244 5/20 0.31
FLT3 P36888 1/20 0.31
TYRO3 Q06418 1/20 0.31
MERTK Q12866 1/20 0.31
GAS6 Q14393 1/20 0.31
PPARA Q07869 2/20 0.31
PLA2G2C Q5R387 1/20 0.31
PPARG P37231 2/20 0.31
SIRT5 Q9NXA8 1/20 0.31
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428950 0.95 PPARA (0.34) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL9428301 0.92
SCHEMBL9428689 0.89 GAA (0.33) KDM4ENPSR1S1PR1S1PR3P2RY12
SCHEMBL9428379 0.89 KMT2A (0.40) KMT2A
SCHEMBL9428700 0.89 KMT2A (0.40) KMT2A
SCHEMBL7475738 0.88
SCHEMBL9428552 0.88 KDM4E (0.38) KDM4EKMT2ASIRT5
SCHEMBL9429013 0.87 KMT2A (0.44) KMT2ANPSR1FLT3TYRO3MERTK
SCHEMBL9429020 0.86
SCHEMBL9429497 0.85 KMT2A (0.44) KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed