Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 11/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385217 | 0.83 | HTR1A (0.48) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9428246 | 0.81 | MEN1 (0.52) | HRH1SIGMAR1CYP1A2CYP2D6TMEM97 | |
| Hydrochloric Acid SCHEMBL9428320 | 0.80 | MEN1 (0.51) | HRH1SIGMAR1CYP1A2CYP2D6TMEM97 | |
| SCHEMBL9428857 | 0.79 | HRH1 (0.48) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9428318 | 0.78 | MEN1 (0.54) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9428656 | 0.77 | ALDH1A1 (0.50) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9429134 | 0.77 | HRH1 (0.43) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9428716 | 0.77 | ALDH1A1 (0.52) | HRH1SIGMAR1CYP1A2CYP2D6MEN1 | |
| SCHEMBL9429643 | 0.76 | MEN1 (0.55) | HRH1SIGMAR1MEN1ALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL9428727 | 0.76 | HRH1 (0.48) | HRH1MEN1ALDH1A1KMT2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |