Sugi Predict

Sugi Predict / Compounds / SCHEMBL9428848

SCHEMBL9428848

SCHEMBL9428848

C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1[C@@H](C)C(=S)Sc1ccccc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.31
▸ FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428362 0.93 FAAH (0.32) ELANEFAAH
SCHEMBL9428847 0.90 ELANE (0.33) ELANEFAAH
SCHEMBL9428764 0.89 ELANE (0.33) ELANEFAAH
SCHEMBL13946276 0.89 ELANE (0.33) ELANEFAAH
SCHEMBL6892231 0.89 ELANE (0.33) ELANEFAAH
SCHEMBL9726095 0.89 ELANE (0.33) ELANEFAAH
SCHEMBL13764795 0.86 FAAH (0.33) ELANEFAAH
SCHEMBL3873801 0.86 FAAH (0.33) ELANEFAAH
SCHEMBL6892042 0.86 FAAH (0.33) ELANEFAAH
SCHEMBL7630397 0.85 ELANE (0.31) ELANEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306816-A Processes for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 — — US disclosed
EP-0499196-A1 Intermediates and process for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-08-19 — — EP disclosed