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SCHEMBL9428362

SCHEMBL9428362

C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1[C@@H](C)C(=S)SC)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 4/20 0.32
▸ ELANE P08246 1/20 0.31
▸ MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428848 0.93 ELANE (0.31) FAAHELANE
SCHEMBL9428847 0.91 ELANE (0.33) FAAHELANEMGLL
SCHEMBL13946276 0.91 ELANE (0.33) FAAHELANEMGLL
SCHEMBL6892231 0.91 ELANE (0.33) FAAHELANEMGLL
SCHEMBL9726095 0.90 ELANE (0.33) FAAHELANEMGLL
SCHEMBL7630397 0.88 ELANE (0.31) FAAHELANE
SCHEMBL6892042 0.87 FAAH (0.33) FAAHELANEMGLL
SCHEMBL3873801 0.87 FAAH (0.33) FAAHELANEMGLL
SCHEMBL13764795 0.87 FAAH (0.33) FAAHELANEMGLL
SCHEMBL9429055 0.87 FAAH (0.34) FAAHELANEMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306816-A Processes for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 — — US disclosed
EP-0499196-A1 Intermediates and process for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-08-19 — — EP disclosed