Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389096 | 0.84 | KCNH2 (0.64) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428920 | 0.74 | SLC22A2 (0.56) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9429448 | 0.69 | SLC22A2 (0.46) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428818 | 0.68 | ADRB1 (0.64) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9385063 | 0.67 | KCNH2 (0.65) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9388704 | 0.67 | KCNH2 (0.89) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428378 | 0.65 | MAPK1 (0.49) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428370 | 0.64 | ADRB1 (0.75) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428374 | 0.64 | ADRB1 (0.75) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9429589 | 0.63 | ADRB1 (0.75) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |