Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429589 | 0.76 | ADRB1 (0.75) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428809 | 0.75 | ADRB1 (0.71) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| Oxalic Acid SCHEMBL9428952 | 0.74 | SLC22A2 (0.71) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428875 | 0.71 | ADRB1 (0.65) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428818 | 0.70 | ADRB1 (0.64) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9428867 | 0.69 | SLC22A2 (0.44) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL6567560 | 0.69 | OPRK1 (0.60) | TAAR1OPRK1DRD2OPRM1DRD3 | |
| SCHEMBL9429027 | 0.68 | TAAR1 (0.66) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| Water SCHEMBL8160723 | 0.68 | OPRK1 (0.58) | TAAR1OPRK1DRD2OPRM1DRD3 | |
| SCHEMBL9389096 | 0.67 | KCNH2 (0.64) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |