Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 10/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9428856 | 0.95 | HRH1 (0.44) | SIGMAR1KCNH2HRH1ADRA1AADRA1D | |
| SCHEMBL9429479 | 0.84 | HRH1 (0.46) | SIGMAR1MEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9429102 | 0.80 | MEN1 (0.44) | MEN1ALDH1A1KMT2AHRH1ADRA1A | |
| SCHEMBL9429487 | 0.79 | SIGMAR1 (0.50) | SIGMAR1MEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9428993 | 0.79 | ALDH1A1 (0.50) | SIGMAR1KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL9428525 | 0.77 | MEN1 (0.48) | MEN1ALDH1A1KMT2AHRH1ADRA1A | |
| SCHEMBL9383794 | 0.76 | SIGMAR1 (0.55) | SIGMAR1MEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9428857 | 0.76 | HRH1 (0.48) | MEN1ALDH1A1KMT2AHRH1ADRA1A | |
| Oxalic Acid SCHEMBL9428762 | 0.76 | HRH1 (0.44) | MEN1ALDH1A1KMT2AHRH1ADRA1A | |
| SCHEMBL9429643 | 0.76 | MEN1 (0.55) | SIGMAR1MEN1ALDH1A1KMT2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |