Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.33 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389910 | 0.81 | SLC22A2 (0.48) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9428964 | 0.76 | MAPK1 (0.49) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9428388 | 0.75 | CYP1A2 (0.49) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9429872 | 0.73 | ADRA1B (0.45) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9428378 | 0.72 | MAPK1 (0.49) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9199477 | 0.70 | MAPK1 (0.73) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9431119 | 0.70 | MAPK1 (0.49) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9205226 | 0.68 | MAPK1 (0.64) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9429605 | 0.68 | TAAR1 (0.45) | MAPK1CYP1A2TAAR1NPSR1TSHR | |
| SCHEMBL9428569 | 0.66 | TAAR1 (0.60) | MAPK1CYP1A2TAAR1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |