SCHEMBL9429166

SCHEMBL9429166

CCCCCCCCON1C(C)(C)CC(C(CCC)Nc2nc(NCC(C)O)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH2 P48735 1/20 0.33
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7475738 0.90
SCHEMBL9428379 0.88 KMT2A (0.40) GBA1
SCHEMBL9428700 0.88 KMT2A (0.40) GBA1
SCHEMBL9429013 0.86 KMT2A (0.44) GBA1
SCHEMBL9427868 0.86 IDH2 (0.36) IDH2GBA1
SCHEMBL9428301 0.86
SCHEMBL9428639 0.85 KMT2A (0.35) IDH2
SCHEMBL9428528 0.85 CDK1 (0.30)
SCHEMBL7456205 0.85 KMT2A (0.35) IDH2
SCHEMBL9428791 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed