SCHEMBL9428700

SCHEMBL9428700

CCCCCCCCON1C(C)(C)CC(C(CCC)Nc2nc(NCCO)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.40
GBA1 P04062 2/20 0.34
SLC29A1 Q99808 1/20 0.34
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428379 1.00 KMT2A (0.40) KMT2AGBA1SLC29A1HRH4
SCHEMBL9429013 0.98 KMT2A (0.44) KMT2AGBA1SLC29A1HRH4
SCHEMBL7475738 0.92
SCHEMBL9428469 0.90 KMT2A (0.33) KMT2A
SCHEMBL9429175 0.89 KDM4E (0.35) KMT2A
SCHEMBL9428098 0.88 HTR7 (0.33) KMT2A
SCHEMBL9429497 0.88 KMT2A (0.44) KMT2A
SCHEMBL9429166 0.88 IDH2 (0.33) GBA1
SCHEMBL9428301 0.87
SCHEMBL9428567 0.87 EHMT2 (0.34) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed