Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428383 | 0.85 | MAPT (0.59) | HTR1A | |
| SCHEMBL9428719 | 0.83 | HRH3 (0.47) | HTR1AHTR2A | |
| SCHEMBL9429574 | 0.82 | HRH1 (0.48) | HTR1A | |
| Hydrochloric Acid SCHEMBL9428866 | 0.82 | HRH1 (0.47) | HTR1A | |
| SCHEMBL9428178 | 0.82 | MAPT (0.55) | HTR1AHTR2A | |
| SCHEMBL9429031 | 0.81 | HTR1A (0.55) | HTR1A | |
| SCHEMBL9429765 | 0.81 | HRH3 (0.52) | HTR1AHTR2A | |
| SCHEMBL9429621 | 0.80 | DRD2 (0.51) | HTR1AHTR2A | |
| SCHEMBL9429697 | 0.80 | DRD2 (0.57) | HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL9429549 | 0.80 | HTR1A (0.54) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |