Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.58 |
| ▸ | CYCS | P99999 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906606 | 0.82 | TOP1 (0.60) | TOP1CYCSABCG2 | |
| SCHEMBL9429433 | 0.82 | TOP1 (0.60) | TOP1CYCSABCG2 | |
| SCHEMBL9429681 | 0.80 | TOP1 (0.70) | TOP1CYCSABCG2 | |
| SCHEMBL8907679 | 0.78 | TOP1 (0.52) | TOP1CYCSABCG2 | |
| SCHEMBL25394852 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2 | |
| SCHEMBL16418477 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2 | |
| SCHEMBL483511 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2 | |
| SCHEMBL25395869 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2 | |
| SCHEMBL29556585 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2 | |
| SCHEMBL8908782 | 0.77 | TOP1 (0.58) | TOP1CYCSABCG2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284647-A | Administering for magnetic resonance imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |