Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429056 | 0.80 | HSD17B10 (0.38) | HIF1AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL499169 | 0.79 | PDE4A (0.44) | KMT2AALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9429760 | 0.79 | TET2 (0.37) | — | |
| SCHEMBL13297310 | 0.79 | GSK3B (0.48) | GSK3BCA12CA2CA9CA4 | |
| SCHEMBL9429538 | 0.78 | FABP3 (0.33) | NPC1 | |
| SCHEMBL267948 | 0.71 | LMNA (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL4648778 | 0.71 | CA12 (0.54) | GSK3BCA12CA2CA9CDC25A | |
| Water SCHEMBL23522818 | 0.70 | LMNA (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL17768421 | 0.70 | LMNA (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL15004685 | 0.70 | LMNA (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284647-A | Administering for magnetic resonance imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |