Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL14977045 | 0.98 | LMNA (0.38) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL267948 | 0.98 | LMNA (0.41) | LMNAENPP2ALDH1A1TSHRNT5E | |
| Water SCHEMBL23522818 | 0.97 | LMNA (0.39) | LMNAENPP2ALDH1A1TSHRNT5E | |
| Water SCHEMBL9870236 | 0.97 | LMNA (0.39) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL20379960 | 0.97 | LMNA (0.39) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL15004685 | 0.97 | LMNA (0.39) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL271881 | 0.92 | TSHR (0.46) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL7258220 | 0.92 | LMNA (0.53) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL10676586 | 0.88 | CA12 (0.44) | ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL8167637 | 0.84 | ENPP2 (0.32) | LMNAENPP2ALDH1A1TSHRNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3220887-A1 | GEL FORMULATIONS FOR LOCAL DRUG RELEASE | Technical University of Denmark (DK) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016079330-A1 | GEL FORMULATIONS FOR LOCAL DRUG RELEASE | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2016-05-26 | — | — | WO | disclosed |
| WO-2016079331-A1 | GEL FORMULATIONS FOR ENHANCING THE EFFECT OF RADIOTHERAPY | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2016-05-26 | — | — | WO | disclosed |