SCHEMBL9429360

SCHEMBL9429360

O=C(O)c1cc2ccc3c(C(=O)O)c(C(=O)O)cc4ccc(c1C(=O)O)c2c43

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
CYP2C19 P33261 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GRIN2D O15399 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
PTPN1 P18031 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LCK P06239 1/20 0.39
WDR5 P61964 1/20 0.38
IDO1 P14902 1/20 0.38
GPR35 Q9HC97 2/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10392526 1.00 CYP1A2 (0.41) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL183076 0.91 KMT2A (0.55) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL9429858 0.89 ALDH1A1 (0.34) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL9429864 0.83 GPR35 (0.41) CYP1A2ALDH1A1HPGDKDM4EGLA
SCHEMBL345964 0.79 MEN1 (0.50) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL9135098 0.78 MEN1 (0.42) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL29393911 0.77 KMT2A (0.45) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL10813708 0.77 KMT2A (0.45) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL9428595 0.77 KMT2A (0.45) CYP1A2MEN1KMT2AALDH1A1HPGD
SCHEMBL29500277 0.77 KMT2A (0.45) CYP1A2MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5301876-A None JP disclosed
US-5294512-A Derivatives of the diimide of pyreno(1,2-c:6,7-c')dipyrroles KONICA CORPORATION (JP) 1994-03-15 US disclosed
JP-H05301876-A NEW PYRENE-BASED COMPOUND AND ITS PRODUCTION AND ELECTROPHOTOGRAPHIC RECEPTOR CONTAINING THE SAME KONICA CORP 1993-11-16 JP disclosed
US-4748099-A Process for forming printing plate using an electrophotographic material for obtaining toner image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-05-31 US disclosed
US-4383089-A Process for the production of polyepoxy silicate resin BLOUNT DAVID H 1983-05-10 US disclosed
US-4383049-A POLYURETHANES BLOUNT DAVID H 1983-05-10 US disclosed
US-4382136-A EPOXIDE, LEWIS ACID BLOUNT DAVID H 1983-05-03 US disclosed
US-4380592-A Process for the production of polyhydroxy lignin-cellulose silicate polymer BLOUNT DAVID H (US) 1983-04-19 US disclosed
US-4377674-A POLYURETHANES; FOAMS; COPOLYMERS; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4377646-A REACTING AN EPOXY COMPOUND, SILICIC ACID, AND A POLYISOCYANATE USING A LEWIS ACID CATALYST; POLYURETHANES; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4376173-A LIGNIN, CELLULOSE, POLYURETHANE FOAM, POLYISOCYANATE BLOUNT DAVID H 1983-03-08 US disclosed
US-4367326-A Process for the production of polyepoxy silicate resins DORSEY & WHITNEY LLP 1983-01-04 US disclosed
US-4357463-A HEATING A SILICON COMPOUND, AN EPOXIDE, A DICARBOXYLIC ACID OR ANHYDRIDE, AND A LEWIS ACID; COATINGS; MOLDING MATERIALS; ADHESIVES BLOUNT DAVID H 1982-11-02 US disclosed
US-3975196-A Photoconductive charge transfer complex for electrophotography PITNEY-BOWES, INC. (US) 1976-08-17 US disclosed