Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 18/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387939 | 0.84 | HRH1 (0.49) | HRH1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9383723 | 0.83 | HRH1 (0.48) | HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428555 | 0.80 | HRH1 (0.49) | HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429278 | 0.79 | HRH1 (0.45) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL9387095 | 0.78 | HRH1 (0.47) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| Oxalic Acid SCHEMBL9384375 | 0.76 | HRH1 (0.46) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| Oxalic Acid SCHEMBL9384371 | 0.76 | HRH1 (0.46) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL9429623 | 0.76 | ALDH1A1 (0.48) | HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429393 | 0.75 | HRH3 (0.43) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL9428524 | 0.75 | HRH1 (0.49) | HRH1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |