Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 13/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429278 | 0.92 | HRH1 (0.45) | ALDH1A1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428763 | 0.84 | KCNA5 (0.48) | HRH1ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL9428874 | 0.83 | HRH1 (0.45) | ALDH1A1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9389886 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HRH1MEN1KMT2APOLB | |
| Oxalic Acid SCHEMBL9385206 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HRH1MEN1KMT2APOLB | |
| Oxalic Acid SCHEMBL9385201 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HRH1MEN1KMT2APOLB | |
| SCHEMBL9429375 | 0.76 | HRH1 (0.49) | HRH1ADRA1DADRA1AADRA1B | |
| Oxalic Acid SCHEMBL9428773 | 0.75 | HRH1 (0.48) | ALDH1A1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429605 | 0.75 | TAAR1 (0.45) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9429396 | 0.74 | HRH3 (0.46) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |