Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.54 |
| ▸ | CYCS | P99999 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908782 | 0.81 | TOP1 (0.58) | TOP1CYCSABCG2ENPP2ESR1 | |
| SCHEMBL9429433 | 0.81 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL8906606 | 0.81 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL9429681 | 0.77 | TOP1 (0.70) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL8907679 | 0.77 | TOP1 (0.52) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL20124911 | 0.75 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2HDAC4 | |
| SCHEMBL28152414 | 0.74 | TOP1 (0.79) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL14174613 | 0.74 | TOP1 (0.79) | TOP1CYCSABCG2ENPP2TLR8 | |
| SCHEMBL29354037 | 0.73 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL709532 | 0.73 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284647-A | Administering for magnetic resonance imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |