Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638527 | 0.87 | SLC6A4 (0.67) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL10638396 | 0.85 | SLC6A4 (0.88) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL11642690 | 0.85 | SLC6A4 (0.64) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL11640206 | 0.84 | SLC6A4 (0.78) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10635558 | 0.84 | SLC6A4 (0.86) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7474814 | 0.84 | SLC6A4 (0.60) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7474818 | 0.84 | SLC6A4 (0.60) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9430393 | 0.83 | SIGMAR1 (0.73) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7721328 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3 | |
| SCHEMBL10573356 | 0.82 | SIGMAR1 (0.64) | SLC6A4SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276035-A | Central nervous system disorders; Parkinson's disease; antidepressant and dopaminergic agent | NOVO NORDISK A/S (DK) | 1994-01-04 | — | — | US | disclosed |