Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429782 | 1.00 | CA2 (0.50) | CA2TSHRCA12CA1CA3 | |
| SCHEMBL9429777 | 1.00 | CA2 (0.50) | CA2TSHRCA12CA1CA3 | |
| SCHEMBL9429445 | 0.73 | CA2 (0.52) | CA2TSHRCA12CA1CA3 | |
| SCHEMBL9429441 | 0.73 | CA2 (0.52) | CA2TSHRCA12CA1CA3 | |
| SCHEMBL9429438 | 0.73 | CA2 (0.52) | CA2TSHRCA12CA1CA3 | |
| SCHEMBL10514135 | 0.72 | CA2 (0.54) | CA2 | |
| SCHEMBL9429883 | 0.72 | CA2 (0.61) | CA2 | |
| SCHEMBL9429518 | 0.72 | CA2 (0.43) | CA2 | |
| SCHEMBL9429738 | 0.72 | CA2 (0.43) | CA2 | |
| SCHEMBL4573053 | 0.72 | CA2 (0.50) | CA2TSHRCA12CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276025-A | Heterobicyclic sulfonamides | MERCK & CO., INC. (US) | 1994-01-04 | — | — | US | disclosed |