Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.61 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512165 | 0.76 | CA2 (1.00) | CA2 | |
| SCHEMBL9040253 | 0.74 | RYR2 (0.44) | CA2RYR2PRKD3PRKD1PRKD2 | |
| SCHEMBL10511944 | 0.74 | CA2 (0.82) | CA2 | |
| SCHEMBL9429777 | 0.72 | CA2 (0.50) | CA2 | |
| SCHEMBL9429779 | 0.72 | CA2 (0.50) | CA2 | |
| SCHEMBL9429618 | 0.72 | CA2 (0.43) | CA2 | |
| SCHEMBL9429738 | 0.72 | CA2 (0.43) | CA2 | |
| SCHEMBL9429782 | 0.72 | CA2 (0.50) | CA2 | |
| SCHEMBL9429518 | 0.72 | CA2 (0.43) | CA2 | |
| SCHEMBL9428610 | 0.71 | CA2 (0.68) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276025-A | Heterobicyclic sulfonamides | MERCK & CO., INC. (US) | 1994-01-04 | — | — | US | disclosed |