Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573638 | 0.87 | LTB4R (0.45) | PPARGPPARADRD2CA12CA1 | |
| SCHEMBL31482066 | 0.87 | MAPT (0.41) | KMT2AATMSMN1; SMN2MAPTDRD2 | |
| SCHEMBL9131385 | 0.83 | PPARA (0.49) | PPARGPPARAMEN1KMT2AATM | |
| SCHEMBL7419392 | 0.82 | ELANE (0.46) | MEN1KMT2AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL6804381 | 0.82 | MAPT (0.50) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL3543244 | 0.81 | MAPT (0.55) | PPARGPPARAMEN1KMT2AATM | |
| SCHEMBL19810724 | 0.80 | NOTUM (0.41) | KMT2ASMN1; SMN2MAPTNQO2NOTUM | |
| SCHEMBL24196337 | 0.80 | XDH (0.54) | MEN1KMT2AATML3MBTL1SMN1; SMN2 | |
| SCHEMBL1525956 | 0.80 | MAPT (0.59) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL6808810 | 0.80 | MAPT (0.59) | MEN1KMT2AATMMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373015-A | Treating hypertension and congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-13 | — | — | US | disclosed |
| US-5354500-A | Optically active carboxylic esters of oxygen-containing heterocycles as doping substances in liquid crystal mixtures and liquid crystal mixtures containing them | HOECHST AKTIENGESELLSCHAFT | 1994-10-11 | — | — | US | disclosed |