Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363204 | 0.86 | PDE4D (0.51) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL9429934 | 0.82 | MEN1 (0.45) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL9067037 | 0.74 | KMT2A (0.53) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL10886902 | 0.73 | MEN1 (0.55) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7437351 | 0.72 | PDE4D (0.52) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7445357 | 0.72 | PDE4A (0.72) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7438293 | 0.72 | KMT2A (0.79) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7439770 | 0.71 | MAPT (0.47) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10888585 | 0.71 | MEN1 (0.77) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7433445 | 0.71 | KMT2A (0.76) | KMT2AMEN1CHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288863-A | Cyclization; reacting hydrazine with an acetonyl-, chloro-, dimethoxybenzophenone | EGIS GYOGYSZERGYAR RT. (HU) | 1994-02-22 | — | — | US | disclosed |