Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.51 |
| ▸ | HTR3B | O95264 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404344 | 0.83 | MAPT (0.38) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9404448 | 0.83 | POLB (0.50) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9404233 | 0.83 | HRH4 (0.51) | SMN1; SMN2HRH4HTR3BHTR3AHTR3E | |
| SCHEMBL9404287 | 0.77 | TSHR (0.44) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9404290 | 0.77 | TSHR (0.44) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5320912 | 0.77 | HTR3B (0.69) | SMN1; SMN2HRH4HTR3BHTR3AHTR3E | |
| Hydrochloric Acid SCHEMBL11740107 | 0.75 | HTR3B (0.68) | SMN1; SMN2HRH4HTR3BHTR3AHTR3E | |
| SCHEMBL24813111 | 0.75 | ABL1 (0.35) | SMN1; SMN2HRH4HTR3BHTR3ATRPV4 | |
| SCHEMBL30047583 | 0.75 | ABL1 (0.35) | SMN1; SMN2HRH4HTR3BHTR3ATRPV4 | |
| SCHEMBL24813514 | 0.75 | KDM4E (0.34) | SMN1; SMN2HRH4HTR3BHTR3ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371080-A | Central nervous system disorders | NOVO NORDISK A/S | 1994-12-06 | — | — | US | disclosed |