Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.85 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.85 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.85 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.85 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516503 | 0.88 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3186630 | 0.88 | PDE4A (0.94) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11361392 | 0.86 | PDE4A (0.91) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3842077 | 0.85 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381259 | 0.85 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381240 | 0.85 | ADORA2B (0.94) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3190853 | 0.85 | ADORA2B (0.92) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381263 | 0.84 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381253 | 0.84 | ADORA2B (0.97) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744388 | 0.84 | ADORA2B (0.97) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469698-A | SEDATIVES, TRANQUILIZERS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-09-04 | — | — | US | claimed |
| US-5338741-A | Cardiotonic agents | NESTEC S.A. (CH) | 1994-08-16 | — | — | US | disclosed |
| EP-0269841-B1 | 1-HYDROXYALKYL XANTHINES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5053433-A | Photodiesterase inhibitor | SOCIETE ANONYME DITE: L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0269841-A1 | 1-Hydroxyalkyl xanthines, processes for their preparation and medicaments containing them | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1988-06-08 | — | — | EP | disclosed |