SCHEMBL9429994

SCHEMBL9429994

Cc1nn(C)c(C(=O)NCc2ccc(OC(F)(F)C(F)OC(F)(F)F)cc2F)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.47
▸ GALR3 O60755 1/20 0.47
▸ NR2F2 P24468 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.39
▸ ALPL P05186 2/20 0.38
▸ ALPI P09923 1/20 0.38
▸ ALPG P10696 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ RECQL P46063 1/20 0.37
▸ GLS O94925 1/20 0.37
▸ RIPK1 Q13546 1/20 0.37
▸ GAA P10253 2/20 0.36
▸ HPGD P15428 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CHRM4 P08173 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9410487 0.92 LMNA (0.48) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410480 0.90 GLS (0.38) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410392 0.86 SMN1; SMN2 (0.62) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410414 0.82 LMNA (0.54) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410493 0.82 EPHX2 (0.40) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410471 0.80 LMNA (0.53) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410468 0.80 LMNA (0.55) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410445 0.76 LMNA (0.47) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410436 0.73 LMNA (0.61) LMNAGALR3NR2F2RAB9AKMT2A
SCHEMBL9410381 0.72 SMN1; SMN2 (0.41) LMNAGALR3NR2F2RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5366991-A Agriculture ENI CHEM SYNTHESIS S.P.A. (IT) 1994-11-22 — — US disclosed
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