Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.52 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.52 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.52 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1181635 | 0.87 | CYP1A1 (0.67) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL1180781 | 0.82 | APP (0.74) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL9428523 | 0.82 | APP (0.73) | CYP3A4CYP2E1CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL147295 | 0.81 | HDAC6 (0.56) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL25094618 | 0.79 | HDAC6 (0.55) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL12093643 | 0.79 | HDAC6 (0.55) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL9429775 | 0.77 | ALDH1A1 (0.50) | CYP3A4CYP2E1CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL29668098 | 0.77 | ALDH1A1 (0.50) | CYP3A4CYP2E1CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL5613367 | 0.76 | HDAC6 (0.71) | HDAC6HSD17B2HSD17B1IKBKB | |
| SCHEMBL27576360 | 0.76 | HDAC6 (0.52) | HDAC6CYP3A4CYP2E1CYP2D6CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269719-A | Urea derivatives as CB1 allosteric modulators | RTI国际 | 2022-04-01 | — | — | CN | disclosed |
| US-5328907-A | Treatment of allograft rejection in mammals and antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5108999-A | For treating inflammation, autoimmune disease or allograft rejection in mammals | SYNTEX (U.S.A.) INC. (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| US-5001124-A | 4-isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-03-19 | — | — | US | disclosed |