Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431922 | 0.88 | MEN1 (0.53) | ALOX5CYSLTR1PDE10A | |
| SCHEMBL9031804 | 0.88 | FFAR1 (0.55) | ALOX5CYSLTR1PPARGPDE10A | |
| SCHEMBL9430730 | 0.87 | ALOX5 (0.50) | ALOX5CYSLTR1ALOX5AP | |
| SCHEMBL9430715 | 0.87 | ALOX5 (0.50) | ALOX5CYSLTR1ALOX5AP | |
| SCHEMBL9431239 | 0.87 | ALOX5 (0.50) | ALOX5CYSLTR1ALOX5AP | |
| SCHEMBL9430547 | 0.87 | ALOX5 (0.50) | ALOX5CYSLTR1ALOX5AP | |
| SCHEMBL9430560 | 0.86 | ALOX5 (0.49) | ALOX5CYSLTR1ALOX5AP | |
| SCHEMBL9033104 | 0.85 | ALOX5 (0.46) | ALOX5CYSLTR1PPARGPDE10A | |
| SCHEMBL9431271 | 0.84 | ALOX5 (0.47) | ALOX5CYSLTR1PPARGALOX5AP | |
| SCHEMBL9430847 | 0.84 | ALOX5 (0.47) | ALOX5CYSLTR1PPARGALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304563-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |