SCHEMBL9430618

SCHEMBL9430618

C=Cc1cccc(Oc2nc(OC)cc(OC)n2)c1C(=O)OCC

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.47
CYP2C9 P11712 3/20 0.47
CYP2C19 P33261 3/20 0.47
CYP3A4 P08684 2/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 2/20 0.44
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161257 0.87 CYP1A2 (0.41) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9211362 0.85 CYP1A2 (0.46) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9294680 0.84 CA12 (0.56) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9622245 0.83 NPSR1 (0.58) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9617886 0.83 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9617887 0.83 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL732024 0.80 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9215028 0.80 CYP1A2 (0.46) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7833574 0.78 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7835212 0.78 ALDH1A1 (0.53) CYP1A2CYP2C9CYP2C19CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4305569-A None JP disclosed
US-5360913-A Herbicides and bioregulators for growth BASF AKTIENGESELLSCHAFT (DE) 1994-11-01 US disclosed
US-5201937-A SALICYCLIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed
JP-H04305569-A SALICYLIC ACIDS DERIVATIVE, INTERMEDIATE FOR PRODUCING THESE COMPOUND AS WELL AS HERBICIDE AND PLANT GROWTH CONTROL AGENT CONTAINING THESE COMPOUND BASF AG 1992-10-28 JP disclosed