Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294680 | 0.83 | CA12 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL732023 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9194907 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9622245 | 0.82 | NPSR1 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9197644 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9730537 | 0.82 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9622353 | 0.81 | NPSR1 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL27377682 | 0.80 | ALDH1A1 (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9430618 | 0.80 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL9195996 | 0.79 | ALDH1A1 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| EP-2675277-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | Bayer Intellectual Property GmbH (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-28 | — | — | US | disclosed |
| US-8318637-B2 | Herbicide/azole combination | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| WO-2012110517-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | WO | disclosed |
| US-20040132621-A1 | Microemulsion concentrates | BAYER CORPSCIENCE GMBH PATENTS AND LICENSING (DE) | 2004-07-08 | — | — | US | disclosed |
| US-20040116300-A1 | Liquid adjuvants | BAYER CROPSCIENCE GMBH (DE) | 2004-06-17 | — | — | US | disclosed |
| US-20040110637-A1 | Method of safening crops using isoxazoline carboxylates | BAYER CROPSCIENCE GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
| US-6693063-B2 | HALOGENATED HYDROXYBENZONITRILE DERIVATIVE WITH SPECIFIC SURFACTANTS | AVENTIS CROPSCIENCE GMBH (DE) | 2004-02-17 | — | — | US | disclosed |
| EP-1365648-A1 | METHOD OF SAFENING CROPS USING ISOXAZOLINE CARBOXYLATES | Bayer CropScience GmbH (DE) | 2003-12-03 | — | — | EP | disclosed |
| US-20020115569-A1 | Herbicidal composition | AVENTIS CROPSCIENCE GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
| WO-2002060256-A1 | METHOD OF SAFENING CROPS USING ISOXAZOLINE CARBOXYLATES | BAYER CROPSCIENCE GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
| US-20020058591-A1 | Herbicidal compositions | BAYER CROPSCIENCE GMBH (DE) | 2002-05-16 | — | — | US | disclosed |
| US-20020016263-A1 | Liquid formulations | AVENTIS CROPSCIENCE GMBH (DE) | 2002-02-07 | — | — | US | disclosed |
| US-6251827-B1 | MIXTURE OF PLANT SAFENING AGENT AND ONE OR MORE PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | CYP1A2 74/4885CYP3A4 202/4885CYP2C9 123/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | CYP1A2 220/4885CYP3A4 824/4885CYP2C9 656/4885 |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | DDT, ING2, DNER | CYP1A2 1091/4885CYP3A4 2239/4885CYP2C9 1573/4885 |
| US-20020016263-A1 | Liquid formulations | SLC25A1, SLC16A1, OTC | CYP1A2 2953/4885CYP3A4 2754/4885CYP2C9 2337/4885 |
| US-20040110637-A1 | Method of safening crops using isoxazoline carboxylates | CYP2W1, CYP4Z1, CYP4X1 | CYP1A2 17/4885CYP3A4 190/4885CYP2C9 81/4885 |
| US-20020058591-A1 | Herbicidal compositions | DDT, HDHD5, GLO1 | CYP1A2 258/4885CYP3A4 1161/4885CYP2C9 503/4885 |
| US-20020115569-A1 | Herbicidal composition | CBR1, DDT, CYP1A1 | CYP1A2 68/4885CYP3A4 775/4885CYP2C9 483/4885 |
| US-20040132621-A1 | Microemulsion concentrates | LIPC, MGLL, SGMS2 | CYP1A2 631/4885CYP3A4 2557/4885CYP2C9 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.