Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214018 | 0.91 | MAOB (0.63) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2785214 | 0.89 | MAOB (0.71) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9430588 | 0.89 | SIRT2 (0.51) | MAOBLRRK2 | |
| SCHEMBL8888358 | 0.87 | LRRK2 (0.63) | MAOBLRRK2MAPTCYP2C9CYP2C19 | |
| SCHEMBL7282913 | 0.84 | MAOB (0.68) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9431235 | 0.84 | SIRT2 (0.54) | MAOBLRRK2L3MBTL1 | |
| SCHEMBL27737196 | 0.81 | MAOB (0.53) | MAOBMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5528125 | 0.81 | MAOB (0.60) | MAOBLRRK2SMN1; SMN2 | |
| SCHEMBL30899826 | 0.81 | MCL1 (0.51) | MAOBMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3219499 | 0.81 | MAOB (0.50) | MAOBMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347050-A | Cardioselective adrenoreceptor blocking agents; prophylaxis and therapy for coronary diseases, glaucoma, migraine | BERTHOLD RICHARD (CH) | 1994-09-13 | — | — | US | disclosed |
| EP-0052072-B1 | 3-AMINOPROPOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-02-20 | — | — | EP | disclosed |