Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 5/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430602 | 1.00 | SLC6A4 (0.50) | SLC6A4LMNASMN1; SMN2POLBTHRB | |
| SCHEMBL9430990 | 1.00 | SLC6A4 (0.50) | SLC6A4LMNASMN1; SMN2POLBTHRB | |
| SCHEMBL9431519 | 0.80 | SLC6A4 (0.48) | SLC6A4LMNASMN1; SMN2POLBTHRB | |
| SCHEMBL9430860 | 0.80 | SLC6A4 (0.51) | SLC6A4LMNASMN1; SMN2NR4A2SCN1A | |
| SCHEMBL13409356 | 0.79 | LMNA (0.56) | LMNASMN1; SMN2POLBTHRBNR4A2 | |
| SCHEMBL7468141 | 0.77 | APP (0.49) | LMNASMN1; SMN2POLBTHRBNR4A2 | |
| SCHEMBL7462754 | 0.76 | APP (0.52) | LMNASMN1; SMN2POLBTHRBNR4A2 | |
| SCHEMBL7465513 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2POLBTHRBNR4A2 | |
| SCHEMBL1147654 | 0.72 | LMNA (0.51) | LMNASMN1; SMN2POLBTHRBNR4A2 | |
| SCHEMBL1702115 | 0.72 | LMNA (0.61) | LMNASMN1; SMN2POLBTHRBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296484-A | Applying fungicide to locus of plant pathogen | DOWELANCO (US) | 1994-03-22 | — | — | US | claimed |
| US-5296484-A | Applying fungicide to locus of plant pathogen | DOWELANCO (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0326328-A2 | Quinoline, quinazoline, and cinnoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |