Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702115 | 0.83 | LMNA (0.61) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL2608853 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL7529202 | 0.81 | NR4A2 (0.59) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL9431519 | 0.81 | SLC6A4 (0.48) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL28641518 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL12762533 | 0.79 | HTR1A (0.52) | GAK | |
| SCHEMBL10377143 | 0.79 | POLB (0.63) | LMNASMN1; SMN2NR4A2SOS2MAPT | |
| SCHEMBL9430990 | 0.79 | SLC6A4 (0.50) | LMNASMN1; SMN2NR4A2SOS2POLB | |
| SCHEMBL9430702 | 0.79 | SLC6A4 (0.50) | LMNASMN1; SMN2NR4A2SOS2POLB | |
| SCHEMBL9430602 | 0.79 | SLC6A4 (0.50) | LMNASMN1; SMN2NR4A2SOS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037266-A | Antibacterial chloroxoquinoline derivative | WANG ZIHOU | 2015-11-11 | — | — | CN | claimed |
| CN-105017145-A | Chloroxoquinoline derivative with anti-tumor activity | WANG ZIHOU | 2015-11-04 | — | — | CN | claimed |
| CN-105037266-A | Antibacterial chloroxoquinoline derivative | WANG ZIHOU | 2015-11-11 | — | — | CN | disclosed |
| CN-105017145-A | Chloroxoquinoline derivative with anti-tumor activity | WANG ZIHOU | 2015-11-04 | — | — | CN | disclosed |
| CN-103864681-B | Chloroxoquinoline derivatives for antibacterial use | WANG ZIHOU (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103864680-B | Chloroxoquinoline derivative with antineoplastic activity | WANG ZIHOU (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103864680-A | Chloroxoquinoline derivative with antineoplastic activity | WANG ZIHOU | 2014-06-18 | — | — | CN | disclosed |
| CN-103864681-A | Chloroxoquinoline derivatives for antibacterial use | WANG ZIHOU | 2014-06-18 | — | — | CN | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |