Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 3/20 | 0.39 |
| ▸ | ADH1A | P07327 | 3/20 | 0.39 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481037 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL7677802 | 0.93 | TSHR (0.62) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL25710164 | 0.91 | TSHR (0.70) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL7674518 | 0.91 | TSHR (0.61) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL1638658 | 0.88 | TSHR (0.55) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL1638660 | 0.86 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL25058741 | 0.84 | TSHR (0.59) | TSHRFAAHTRPV1ALDH1A1ADH1C | |
| SCHEMBL22920282 | 0.84 | TSHR (0.59) | TSHRFAAHTRPV1ALDH1A1ADH1C | |
| SCHEMBL25856420 | 0.84 | TSHR (0.59) | TSHRFAAHTRPV1ALDH1A1ADH1C | |
| SCHEMBL22642669 | 0.84 | TSHR (0.59) | TSHRFAAHTRPV1ALDH1A1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |