Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046626 | 0.98 | TAAR1 (0.55) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL900638 | 0.94 | TAAR1 (0.59) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL1044897 | 0.85 | TAAR1 (0.63) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL6002759 | 0.83 | TAAR1 (0.47) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL15061376 | 0.81 | MAOB (0.68) | — | |
| SCHEMBL2094562 | 0.80 | TAAR1 (0.49) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL3371633 | 0.80 | TAAR1 (0.74) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL1043920 | 0.80 | TAAR1 (0.57) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL1043921 | 0.80 | TAAR1 (0.57) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL12693653 | 0.80 | LPL (0.61) | TAAR1SLC6A3DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347050-A | Cardioselective adrenoreceptor blocking agents; prophylaxis and therapy for coronary diseases, glaucoma, migraine | BERTHOLD RICHARD (CH) | 1994-09-13 | — | — | US | disclosed |
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4425362-A | CARDIOVASCULAR DISORDERS, ADRENERGIC BLOCKING AGENTS | SANDOZ LTD. (CH) | 1984-01-10 | — | — | US | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0035228-A1 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4085139-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |